O₂ universum is located in Prague, one of the most beautiful cities in the world. The complex is situated in north-eastern part of the city centre. It occupies an advantageous position between the interior road ring, which provides comfortable transport possibilities, and the external ring road, which allows a quick connection to the outgoing motorway and the international highway network. The O2 universum entrance is located from south way from Ceskomoravska St.